OK: Found an XML parser.
OK: Support for GZIP encoding.
OK: Support for character munging.

Notice: MagpieRSS [debug] Returning STALE object for http://moustachebrothers.com/feed in /home/morrisc/public_html/rep/rss/rss_fetch.inc on line 243

Example Output

Channel: Moustache Brothers

RSS URL:

Parsed Results (var_dump'ed)

object(MagpieRSS)#2 (23) {
  ["parser"]=>
  int(0)
  ["current_item"]=>
  array(0) {
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  ["items"]=>
  array(10) {
    [0]=>
    array(11) {
      ["title"]=>
      string(58) "Twisting elusive quantum particles with a quantum computer"
      ["link"]=>
      string(89) "https://moustachebrothers.com/twisting-elusive-quantum-particles-with-a-quantum-computer/"
      ["dc"]=>
      array(1) {
        ["creator"]=>
        string(12) "Tony Grantly"
      }
      ["pubdate"]=>
      string(31) "Fri, 03 Dec 2021 12:45:06 +0000"
      ["category"]=>
      string(49) "Health And ScienceelusiveparticlesquantumTwisting"
      ["guid"]=>
      string(37) "https://moustachebrothers.com/?p=8818"
      ["description"]=>
      string(584) "Journal Reference: K. J. Satzinger, Y.-J Liu, A. Smith, C. Knapp, M. Newman, C. Jones, Z. Chen, C. Quintana, X. Mi, A. Dunsworth, C. Gidney, I. Aleiner, F. Arute, K. Arya, J. Atalaya, R. Babbush, J. C. Bardin, R. Barends, J. Basso, A. Bengtsson, A. Bilmes, M. Broughton, B. B. Buckley, D. A. Buell, B. ... Read more"
      ["content"]=>
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        string(5241) "

Journal Reference:

  1. K. J. Satzinger, Y.-J Liu, A. Smith, C. Knapp, M. Newman, C. Jones, Z. Chen, C. Quintana, X. Mi, A. Dunsworth, C. Gidney, I. Aleiner, F. Arute, K. Arya, J. Atalaya, R. Babbush, J. C. Bardin, R. Barends, J. Basso, A. Bengtsson, A. Bilmes, M. Broughton, B. B. Buckley, D. A. Buell, B. Burkett, N. Bushnell, B. Chiaro, R. Collins, W. Courtney, S. Demura, A. R. Derk, D. Eppens, C. Erickson, L. Faoro, E. Farhi, A. G. Fowler, B. Foxen, M. Giustina, A. Greene, J. A. Gross, M. P. Harrigan, S. D. Harrington, J. Hilton, S. Hong, T. Huang, W. J. Huggins, L. B. Ioffe, S. V. Isakov, E. Jeffrey, Z. Jiang, D. Kafri, K. Kechedzhi, T. Khattar, S. Kim, P. V. Klimov, A. N. Korotkov, F. Kostritsa, D. Landhuis, P. Laptev, A. Locharla, E. Lucero, O. Martin, J. R. McClean, M. McEwen, K. C. Miao, M. Mohseni, S. Montazeri, W. Mruczkiewicz, J. Mutus, O. Naaman, M. Neeley, C. Neill, M. Y. Niu, T. E. O’Brien, A. Opremcak, B. Pató, A. Petukhov, N. C. Rubin, D. Sank, V. Shvarts, D. Strain, M. Szalay, B. Villalonga, T. C. White, Z. Yao, P. Yeh, J. Yoo, A. Zalcman, H. Neven, S. Boixo, A. Megrant, Y. Chen, J. Kelly, V. Smelyanskiy, A. Kitaev, M. Knap, F. Pollmann, P. Roushan. Realizing topologically ordered states on a quantum processor. Science, 2021; 374 (6572): 1237 DOI: 10.1126/science.abi8378

What would it be like if we lived in a flat two-dimensional world? Physicists predict that quantum mechanics would be even stranger in that case resulting in exotic particles — so-called “anyons” — that cannot exist in the three-dimensional world we live in. This unfamiliar world is not just a curiosity but may be key to unlocking quantum materials and technologies of the future.

In collaboration with the Google Quantum AI team scientists from the Technical University of Munich and the University of Nottingham used a highly controllable quantum processor to simulate such states of quantum matter. Their results appear in the current issue of the scientific journal Science.

Emergent quantum particles in two-dimensional systems

All particles in our universe come in two flavors, bosons or fermions. In the three-dimensional world we live in, this observation stands firm. However, it was theoretically predicted almost 50 years ago that other types of particles, dubbed anyons, could exist when matter is confined to two dimensions.

While these anyons do not appear as elementary particles in our universe, it turns out that anyonic particles can emerge as collective excitations in so-called topological phases of matter, for which the Nobel prize was awarded in 2016.

“Twisting pairs of these anyons by moving them around one another in the simulation unveils their exotic properties — physicists call it braiding statistics,” says Dr. Adam Smith from the University of Nottingham.

A simple picture for these collective excitations is “the wave” in a stadium crowd — it has a well-defined position, but it cannot exist without the thousands of people that make up the crowd. However, realizing and simulating such topologically ordered states experimentally has proven to be extremely challenging.

Quantum processors as a platform for controlled quantum simulations

In landmark experiments, the teams from TUM, Google Quantum AI, and the University of Nottingham programmed Google’s quantum processor to simulate these two-dimensional states of quantum matter. “Google’s quantum processor named ‘Sycamore’ can be precisely controlled and is a well-isolated quantum system, which are key requirements for performing quantum computations,” says Kevin Satzinger, a scientist from the Google team.

The researchers came up with a quantum algorithm to realize a state with topological order, which was confirmed by simulating the creation of anyon excitations and twisting them around one another. Fingerprints from long-range quantum entanglement could be confirmed in their study. As a possible application, such topologically ordered states can be used to improve quantum computers by realizing new ways of error correction. First steps toward this goal have already been achieved in their work.

“Near term quantum processors will represent an ideal platform to explore the physics of exotic quantum phases matter,” says Prof. Frank Pollmann from TUM. “In the near future, quantum processors promise to solve problems that are beyond the reach of current classical supercomputers.”

We would love to say thanks to the author of this article for this incredible web content

Twisting elusive quantum particles with a quantum computer

" } ["summary"]=> string(584) "Journal Reference: K. J. Satzinger, Y.-J Liu, A. Smith, C. Knapp, M. Newman, C. Jones, Z. Chen, C. Quintana, X. Mi, A. Dunsworth, C. Gidney, I. Aleiner, F. Arute, K. Arya, J. Atalaya, R. Babbush, J. C. Bardin, R. Barends, J. Basso, A. Bengtsson, A. Bilmes, M. Broughton, B. B. Buckley, D. A. Buell, B. ... Read more" ["atom_content"]=> string(5241) "

Journal Reference:

  1. K. J. Satzinger, Y.-J Liu, A. Smith, C. Knapp, M. Newman, C. Jones, Z. Chen, C. Quintana, X. Mi, A. Dunsworth, C. Gidney, I. Aleiner, F. Arute, K. Arya, J. Atalaya, R. Babbush, J. C. Bardin, R. Barends, J. Basso, A. Bengtsson, A. Bilmes, M. Broughton, B. B. Buckley, D. A. Buell, B. Burkett, N. Bushnell, B. Chiaro, R. Collins, W. Courtney, S. Demura, A. R. Derk, D. Eppens, C. Erickson, L. Faoro, E. Farhi, A. G. Fowler, B. Foxen, M. Giustina, A. Greene, J. A. Gross, M. P. Harrigan, S. D. Harrington, J. Hilton, S. Hong, T. Huang, W. J. Huggins, L. B. Ioffe, S. V. Isakov, E. Jeffrey, Z. Jiang, D. Kafri, K. Kechedzhi, T. Khattar, S. Kim, P. V. Klimov, A. N. Korotkov, F. Kostritsa, D. Landhuis, P. Laptev, A. Locharla, E. Lucero, O. Martin, J. R. McClean, M. McEwen, K. C. Miao, M. Mohseni, S. Montazeri, W. Mruczkiewicz, J. Mutus, O. Naaman, M. Neeley, C. Neill, M. Y. Niu, T. E. O’Brien, A. Opremcak, B. Pató, A. Petukhov, N. C. Rubin, D. Sank, V. Shvarts, D. Strain, M. Szalay, B. Villalonga, T. C. White, Z. Yao, P. Yeh, J. Yoo, A. Zalcman, H. Neven, S. Boixo, A. Megrant, Y. Chen, J. Kelly, V. Smelyanskiy, A. Kitaev, M. Knap, F. Pollmann, P. Roushan. Realizing topologically ordered states on a quantum processor. Science, 2021; 374 (6572): 1237 DOI: 10.1126/science.abi8378

What would it be like if we lived in a flat two-dimensional world? Physicists predict that quantum mechanics would be even stranger in that case resulting in exotic particles — so-called “anyons” — that cannot exist in the three-dimensional world we live in. This unfamiliar world is not just a curiosity but may be key to unlocking quantum materials and technologies of the future.

In collaboration with the Google Quantum AI team scientists from the Technical University of Munich and the University of Nottingham used a highly controllable quantum processor to simulate such states of quantum matter. Their results appear in the current issue of the scientific journal Science.

Emergent quantum particles in two-dimensional systems

All particles in our universe come in two flavors, bosons or fermions. In the three-dimensional world we live in, this observation stands firm. However, it was theoretically predicted almost 50 years ago that other types of particles, dubbed anyons, could exist when matter is confined to two dimensions.

While these anyons do not appear as elementary particles in our universe, it turns out that anyonic particles can emerge as collective excitations in so-called topological phases of matter, for which the Nobel prize was awarded in 2016.

“Twisting pairs of these anyons by moving them around one another in the simulation unveils their exotic properties — physicists call it braiding statistics,” says Dr. Adam Smith from the University of Nottingham.

A simple picture for these collective excitations is “the wave” in a stadium crowd — it has a well-defined position, but it cannot exist without the thousands of people that make up the crowd. However, realizing and simulating such topologically ordered states experimentally has proven to be extremely challenging.

Quantum processors as a platform for controlled quantum simulations

In landmark experiments, the teams from TUM, Google Quantum AI, and the University of Nottingham programmed Google’s quantum processor to simulate these two-dimensional states of quantum matter. “Google’s quantum processor named ‘Sycamore’ can be precisely controlled and is a well-isolated quantum system, which are key requirements for performing quantum computations,” says Kevin Satzinger, a scientist from the Google team.

The researchers came up with a quantum algorithm to realize a state with topological order, which was confirmed by simulating the creation of anyon excitations and twisting them around one another. Fingerprints from long-range quantum entanglement could be confirmed in their study. As a possible application, such topologically ordered states can be used to improve quantum computers by realizing new ways of error correction. First steps toward this goal have already been achieved in their work.

“Near term quantum processors will represent an ideal platform to explore the physics of exotic quantum phases matter,” says Prof. Frank Pollmann from TUM. “In the near future, quantum processors promise to solve problems that are beyond the reach of current classical supercomputers.”

We would love to say thanks to the author of this article for this incredible web content

Twisting elusive quantum particles with a quantum computer

" ["date_timestamp"]=> int(1638535506) } [1]=> array(11) { ["title"]=> string(26) "Why cannabis smells skunky" ["link"]=> string(57) "https://moustachebrothers.com/why-cannabis-smells-skunky/" ["dc"]=> array(1) { ["creator"]=> string(12) "Tony Grantly" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 11:28:12 +0000" ["category"]=> string(38) "Health And Sciencecannabisskunkysmells" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8813" ["description"]=> string(566) "Journal Reference: Iain W. H. Oswald, Marcos A. Ojeda, Ryan J. Pobanz, Kevin A. Koby, Anthony J. Buchanan, Josh Del Rosso, Mario A. Guzman, Thomas J. Martin. Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography. ACS Omega, 2021; 6 (47): 31667 DOI: 10.1021/acsomega.1c04196 Cannabis sativa ... Read more" ["content"]=> array(1) { ["encoded"]=> string(3846) "

Journal Reference:

  1. Iain W. H. Oswald, Marcos A. Ojeda, Ryan J. Pobanz, Kevin A. Koby, Anthony J. Buchanan, Josh Del Rosso, Mario A. Guzman, Thomas J. Martin. Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography. ACS Omega, 2021; 6 (47): 31667 DOI: 10.1021/acsomega.1c04196

Cannabis sativa L. produces more than 200 known aroma compounds. Prior studies have focused mainly on terpenoids — molecules that range in odor from fuel-like to woody, citrusy or floral. Different cannabis cultivars have diverse mixtures of these compounds that contribute to their unique aromas. However, although terpenoids are the most abundant aroma compounds in cannabis, there is little evidence that they provide the underlying skunk-like smell of many cultivars. Skunks use several VSCs in their smelly defense sprays, so Iain Oswald and colleagues suspected that there could be similar molecules in cannabis. The team decided to use sensitive analytical techniques to find out.

The researchers analyzed flowers from 13 cannabis cultivars using a custom-built 2D gas chromatography system with three different types of detectors. Then, a four-person panel ranked the pungency of the cultivars on a scale from 0 to 10. The most pungent one, called Bacio Gelato, had the highest concentration of VSCs. The team identified seven VSCs in this cultivar, some of which were also present in other cultivars. Five of the VSCs contained the prenyl functional group and had skunk-like or sulfuric aromas. One compound in particular, 3-methyl-2-butene-1-thiol, referred to as VSC3, was the most abundant VSC in the cultivars that the panel reported to be most pungent. This compound has previously been implicated in the flavor and aroma of “skunked beer” — beer that goes bad after being exposed to UV light.

To confirm that VSC3 was the main source of the skunk-like aroma, the team added it to a mixture of 10 other major aroma compounds from cannabis, producing a combined odor very similar to the characteristic scent of cannabis. They also detected VSC3 in cannabis concentrates, such as those used for vaping. Finally, in greenhouse experiments, the researchers determined that the prenylated VSCs increased significantly toward the end of the flowering stage of cannabis growth, reached a maximum during curing and then dropped substantially after 10 days of storage. Because the molecular structures of the VSCs resemble compounds from garlic that have anti-cancer and cardioprotective effects, the new family of prenylated odor molecules should be investigated for medicinal properties, the researchers say.

The authors do not acknowledge any external funding sources for this study. Three of the authors have filed a patent related to the findings.

We want to give thanks to the author of this write-up for this remarkable web content

Why cannabis smells skunky

" } ["summary"]=> string(566) "Journal Reference: Iain W. H. Oswald, Marcos A. Ojeda, Ryan J. Pobanz, Kevin A. Koby, Anthony J. Buchanan, Josh Del Rosso, Mario A. Guzman, Thomas J. Martin. Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography. ACS Omega, 2021; 6 (47): 31667 DOI: 10.1021/acsomega.1c04196 Cannabis sativa ... Read more" ["atom_content"]=> string(3846) "

Journal Reference:

  1. Iain W. H. Oswald, Marcos A. Ojeda, Ryan J. Pobanz, Kevin A. Koby, Anthony J. Buchanan, Josh Del Rosso, Mario A. Guzman, Thomas J. Martin. Identification of a New Family of Prenylated Volatile Sulfur Compounds in Cannabis Revealed by Comprehensive Two-Dimensional Gas Chromatography. ACS Omega, 2021; 6 (47): 31667 DOI: 10.1021/acsomega.1c04196

Cannabis sativa L. produces more than 200 known aroma compounds. Prior studies have focused mainly on terpenoids — molecules that range in odor from fuel-like to woody, citrusy or floral. Different cannabis cultivars have diverse mixtures of these compounds that contribute to their unique aromas. However, although terpenoids are the most abundant aroma compounds in cannabis, there is little evidence that they provide the underlying skunk-like smell of many cultivars. Skunks use several VSCs in their smelly defense sprays, so Iain Oswald and colleagues suspected that there could be similar molecules in cannabis. The team decided to use sensitive analytical techniques to find out.

The researchers analyzed flowers from 13 cannabis cultivars using a custom-built 2D gas chromatography system with three different types of detectors. Then, a four-person panel ranked the pungency of the cultivars on a scale from 0 to 10. The most pungent one, called Bacio Gelato, had the highest concentration of VSCs. The team identified seven VSCs in this cultivar, some of which were also present in other cultivars. Five of the VSCs contained the prenyl functional group and had skunk-like or sulfuric aromas. One compound in particular, 3-methyl-2-butene-1-thiol, referred to as VSC3, was the most abundant VSC in the cultivars that the panel reported to be most pungent. This compound has previously been implicated in the flavor and aroma of “skunked beer” — beer that goes bad after being exposed to UV light.

To confirm that VSC3 was the main source of the skunk-like aroma, the team added it to a mixture of 10 other major aroma compounds from cannabis, producing a combined odor very similar to the characteristic scent of cannabis. They also detected VSC3 in cannabis concentrates, such as those used for vaping. Finally, in greenhouse experiments, the researchers determined that the prenylated VSCs increased significantly toward the end of the flowering stage of cannabis growth, reached a maximum during curing and then dropped substantially after 10 days of storage. Because the molecular structures of the VSCs resemble compounds from garlic that have anti-cancer and cardioprotective effects, the new family of prenylated odor molecules should be investigated for medicinal properties, the researchers say.

The authors do not acknowledge any external funding sources for this study. Three of the authors have filed a patent related to the findings.

We want to give thanks to the author of this write-up for this remarkable web content

Why cannabis smells skunky

" ["date_timestamp"]=> int(1638530892) } [2]=> array(11) { ["title"]=> string(61) "Incredible Memphis: Wins by 73! Unstoppable suns, Bucks stop" ["link"]=> string(88) "https://moustachebrothers.com/incredible-memphis-wins-by-73-unstoppable-suns-bucks-stop/" ["dc"]=> array(1) { ["creator"]=> string(10) "Holly June" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 11:22:36 +0000" ["category"]=> string(44) "NBABucksIncredibleMemphisSunsUnstoppablewins" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8807" ["description"]=> string(657) "The Grizzlies establish the new NBA record for success with greater waste by destroying the hapless Thunder. Phoenix extends the streak to 18 by beating Detroit. Toronto folds Milwaukee, devoid of Antetokounmpo Simone Sandri @simonesandri December 3 – new york The Grizzlies establish a new NBA record by overcoming the unfortunate Thunder by an incredible ... Read more" ["content"]=> array(1) { ["encoded"]=> string(5906) "

The Grizzlies establish the new NBA record for success with greater waste by destroying the hapless Thunder. Phoenix extends the streak to 18 by beating Detroit. Toronto folds Milwaukee, devoid of Antetokounmpo

Simone Sandri

@simonesandri

The Grizzlies establish a new NBA record by overcoming the unfortunate Thunder by an incredible 73-point margin, the Bucks are knocked out in Toronto while Phoenix wins the 18th consecutive success by overtaking Detroit.

memphis-oklahoma city 152-79

It is useless to double check the result, it is correct. The Grizzlies (12-10) destroy the Thunder (6-16) and establish a new NBA record: the margin of 73 points is the highest in the history of the league and surpasses the previous record set by the Cavaliers (68 in a 148-80 against the Heat on December 17, 1991). Memphis was also without its best player, Ja Morant, who was out with a left knee problem. The Grizzlies shoot with an incredible 62.5% from the field and 52.8% from long range and score nine players in double figures.

Memphis: Jackson Jr. 27 (3/4, 6/7, 3/3 tl), Melton 19, Aldama 18. Rebounds: Aldama 10. Assists: Jones 9.

Oklahoma City: Dort 15 (1/2, 2/6, 7/8 tl), Mann, Jerome, Muscala 12. Rimbalzi: Muscala, Robinson Earl 5. Assist: Jerome 4.

toronto-milwaukee 97-93

With Giannis Antetokounmpo as a precaution in the pits due to a muscle problem, the reigning champions are knocked out in Toronto. Milwaukee (14-9) fails to contain an excellent VanVleet, who changes gears in the fourth fraction, signs 13 of his 29 points and leads the Raptors (10-13) to success. The streak of eight consecutive victories for the Bucks comes to an end, also without Brook Lopez, who was operated on yesterday on his back. It will stay out for a long time. Siakam and rookie Barnes also did well.

Toronto: VanVleet 29 (4/7, 5/10, 6/6 tl), Siakam 20, Barnes 13. Rebounds: Trent Jr., Achiuwa, Siakam 8. Assists: VanVleet, Barnes, Siakam 4.

Milwaukee: Holiday 26 (6/14, 4/5, 2/5 tl), Middleton 22, Portis 15. Rimbalzi: Portis 11. Assist: Holiday 8.

phoenix-detroit 114-103

No Booker, no problem. Even without his best scorer Phoenix (19-3) continues the march passing the Pistons (4-18) and thus conquering the 18th consecutive success. CP3 and his companions then set a new record for the Arizona franchise. After dominating the first half, the Suns fall asleep in the third fraction, Detroit returns to the game with a 17-0 run but as soon as the home team senses the danger, it resumes playing and takes off.

Phoenix: Johnson 19 (3/5, 4/6, 1/2 tl), Payne 19 (7/13, 1/1, 2/2 tl), Bridges 18. Rimbalzi: Ayton 12. Assist: Paul 12.

Detroit: Grant 34 (8/16, 2/3, 12/14 tl), Cunningham 19, Stewart 14. Rimbalzi: Stewart 12. Assist: Cunningham 5.

portland-san antonio 83-114

Third consecutive success for the Spurs (7-13) who get rid of the Blazers (11-12) without any major problems, without their leader Lillard. The Texan team dominated far and wide and started the credits with a 12-0 run in the middle of the last quarter. Very good performance by Forbes who gives coach Popovich 18 points in just 15 ‘from the bench.

Portland: McCollum 16 (5/12, 2/6, 0/2 tl), Powell 16 (1/7, 2/5, 8/7 tl), McLemore 11. Rimbalzi: Nurkic 7. Assist: Smith Jr. 5.

San antonio: Forbes 18 (4/4, 3/5, 1/1 tl), McDermott 16, Murray 15. Rebounds: Poeltl 9. Assists: Murray 13.

We want to thank the author of this article for this remarkable web content

Incredible Memphis: Wins by 73! Unstoppable suns, Bucks stop

" } ["summary"]=> string(657) "The Grizzlies establish the new NBA record for success with greater waste by destroying the hapless Thunder. Phoenix extends the streak to 18 by beating Detroit. Toronto folds Milwaukee, devoid of Antetokounmpo Simone Sandri @simonesandri December 3 – new york The Grizzlies establish a new NBA record by overcoming the unfortunate Thunder by an incredible ... Read more" ["atom_content"]=> string(5906) "

The Grizzlies establish the new NBA record for success with greater waste by destroying the hapless Thunder. Phoenix extends the streak to 18 by beating Detroit. Toronto folds Milwaukee, devoid of Antetokounmpo

Simone Sandri

@simonesandri

The Grizzlies establish a new NBA record by overcoming the unfortunate Thunder by an incredible 73-point margin, the Bucks are knocked out in Toronto while Phoenix wins the 18th consecutive success by overtaking Detroit.

memphis-oklahoma city 152-79

It is useless to double check the result, it is correct. The Grizzlies (12-10) destroy the Thunder (6-16) and establish a new NBA record: the margin of 73 points is the highest in the history of the league and surpasses the previous record set by the Cavaliers (68 in a 148-80 against the Heat on December 17, 1991). Memphis was also without its best player, Ja Morant, who was out with a left knee problem. The Grizzlies shoot with an incredible 62.5% from the field and 52.8% from long range and score nine players in double figures.

Memphis: Jackson Jr. 27 (3/4, 6/7, 3/3 tl), Melton 19, Aldama 18. Rebounds: Aldama 10. Assists: Jones 9.

Oklahoma City: Dort 15 (1/2, 2/6, 7/8 tl), Mann, Jerome, Muscala 12. Rimbalzi: Muscala, Robinson Earl 5. Assist: Jerome 4.

toronto-milwaukee 97-93

With Giannis Antetokounmpo as a precaution in the pits due to a muscle problem, the reigning champions are knocked out in Toronto. Milwaukee (14-9) fails to contain an excellent VanVleet, who changes gears in the fourth fraction, signs 13 of his 29 points and leads the Raptors (10-13) to success. The streak of eight consecutive victories for the Bucks comes to an end, also without Brook Lopez, who was operated on yesterday on his back. It will stay out for a long time. Siakam and rookie Barnes also did well.

Toronto: VanVleet 29 (4/7, 5/10, 6/6 tl), Siakam 20, Barnes 13. Rebounds: Trent Jr., Achiuwa, Siakam 8. Assists: VanVleet, Barnes, Siakam 4.

Milwaukee: Holiday 26 (6/14, 4/5, 2/5 tl), Middleton 22, Portis 15. Rimbalzi: Portis 11. Assist: Holiday 8.

phoenix-detroit 114-103

No Booker, no problem. Even without his best scorer Phoenix (19-3) continues the march passing the Pistons (4-18) and thus conquering the 18th consecutive success. CP3 and his companions then set a new record for the Arizona franchise. After dominating the first half, the Suns fall asleep in the third fraction, Detroit returns to the game with a 17-0 run but as soon as the home team senses the danger, it resumes playing and takes off.

Phoenix: Johnson 19 (3/5, 4/6, 1/2 tl), Payne 19 (7/13, 1/1, 2/2 tl), Bridges 18. Rimbalzi: Ayton 12. Assist: Paul 12.

Detroit: Grant 34 (8/16, 2/3, 12/14 tl), Cunningham 19, Stewart 14. Rimbalzi: Stewart 12. Assist: Cunningham 5.

portland-san antonio 83-114

Third consecutive success for the Spurs (7-13) who get rid of the Blazers (11-12) without any major problems, without their leader Lillard. The Texan team dominated far and wide and started the credits with a 12-0 run in the middle of the last quarter. Very good performance by Forbes who gives coach Popovich 18 points in just 15 ‘from the bench.

Portland: McCollum 16 (5/12, 2/6, 0/2 tl), Powell 16 (1/7, 2/5, 8/7 tl), McLemore 11. Rimbalzi: Nurkic 7. Assist: Smith Jr. 5.

San antonio: Forbes 18 (4/4, 3/5, 1/1 tl), McDermott 16, Murray 15. Rebounds: Poeltl 9. Assists: Murray 13.

We want to thank the author of this article for this remarkable web content

Incredible Memphis: Wins by 73! Unstoppable suns, Bucks stop

" ["date_timestamp"]=> int(1638530556) } [3]=> array(11) { ["title"]=> string(62) "Formula 1: Mercedes promises “grenade” for the final spurt" ["link"]=> string(86) "https://moustachebrothers.com/formula-1-mercedes-promises-grenade-for-the-final-spurt/" ["dc"]=> array(1) { ["creator"]=> string(8) "Ann Moon" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 10:34:36 +0000" ["category"]=> string(45) "SportfinalFormulagrenadeMercedespromisesspurt" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8801" ["description"]=> string(594) "Before the Formula 1 premiere on Sunday (6.30 p.m. CET) in Jeddah, Hamilton shone three weeks ago at the GP in Brazil with a fresh engine, but then in Qatar the engine was not used and saved. “We are on the hunt, more motivated than ever and are looking forward to our racing debut in ... Read more" ["content"]=> array(1) { ["encoded"]=> string(4674) "

Before the Formula 1 premiere on Sunday (6.30 p.m. CET) in Jeddah, Hamilton shone three weeks ago at the GP in Brazil with a fresh engine, but then in Qatar the engine was not used and saved. “We are on the hunt, more motivated than ever and are looking forward to our racing debut in Saudi Arabia,” said Wolff before the first laps on the new Jeddah Corniche Circuit, which should be Mercedes with its long full throttle and fast corners.

After two consecutive Grand Prix victories, Hamilton reduced his deficit to eight points, but Verstappen could still become world champion for the first time this Sunday. “I feel calm. I know that I’ll always try to do my best, ”said the Dutchman. “It will be an exciting end to the season,” said the 24-year-old.

Preview of Formula 1 duel in Jeddah

The penultimate Formula 1 Grand Prix in Jeddah at the weekend will again deliver a duel between Max Verstappen and Lewis Hamilton.

More exciting than it has been for a long time

Ralf Schumacher is hoping for a sporty, fair decision in the exciting World Cup in 2021. “This is a mega season. One of the most exciting in a long time. It would be a shame if the FIA ​​(the international automobile association, note) had to decide who will be world champion, ”said the former Formula 1 driver and brother of record world champion Michael Schumacher. Ex-F1 driver Christian Klien agreed. “We only experienced verbal taunts between the teams, not between the drivers. They behave professionally and do their job. “

Verstappen holt Title with …

  • Victory plus extra point, Hamilton a maximum of sixth
  • Victory without extra point, Hamilton maximum seventh
  • Second place plus extra point, Hamilton a maximum of tenth
  • Second place without extra point, Hamilton without points

With his eighth title win, Hamilton could put himself at the top of the all-time ranking, ahead of Michael Schumacher, and continue as the sole record world champion. “Lewis is running out of time and nobody knows how the car will go next year,” said Schumacher and advises that it be better to clinch the eighth title this year. In his opinion, Hamilton therefore has more to lose. “The pressure is more on Lewis. And it is difficult to estimate how much support he will get from Valtteri Bottas. “

Hamilton can’t go all out

Red Bull, on the other hand, is building on four cars, after Sergio Perez and the drivers of the second Mateschitz team, Alpha Tauri Verstappen, are unlikely to get in the way. Schumacher is convinced that if there is a risk of collision, Hamilton will rather withdraw, as he did in Brazil. “Lewis has to be very careful. Because if it crashes, Max could take it. I hope not, but now it’s all about. “

According to the German, drivers and teams are nervous. “But it is nice to see that it goes to the last race.” Without his – partly through no fault of his – failures, Verstappen would have long been world champion, said Schumacher. Going back five places on the starting grid with an engine change and having a powerful engine like Mercedes in the last race in Abu Dhabi is definitely an option. But it’s not just about the engine. “Mercedes has been better lately, especially when it comes to handling the tires.”

He would like to spare himself and the spectators further objections from the two teams fighting for the title, said Schumacher. “It would be a shame to have this exciting duel.” In the past, Bernie Ecclestone had a different approach. “He came in to us and said that whoever interferes won’t get a super license next year.” A title duel is tough, but it has to be fair. “You have to be able to look each other in the eye. That should work this time too, the two of them will work it out between themselves. “

We wish to thank the writer of this post for this awesome web content

Formula 1: Mercedes promises “grenade” for the final spurt

" } ["summary"]=> string(594) "Before the Formula 1 premiere on Sunday (6.30 p.m. CET) in Jeddah, Hamilton shone three weeks ago at the GP in Brazil with a fresh engine, but then in Qatar the engine was not used and saved. “We are on the hunt, more motivated than ever and are looking forward to our racing debut in ... Read more" ["atom_content"]=> string(4674) "

Before the Formula 1 premiere on Sunday (6.30 p.m. CET) in Jeddah, Hamilton shone three weeks ago at the GP in Brazil with a fresh engine, but then in Qatar the engine was not used and saved. “We are on the hunt, more motivated than ever and are looking forward to our racing debut in Saudi Arabia,” said Wolff before the first laps on the new Jeddah Corniche Circuit, which should be Mercedes with its long full throttle and fast corners.

After two consecutive Grand Prix victories, Hamilton reduced his deficit to eight points, but Verstappen could still become world champion for the first time this Sunday. “I feel calm. I know that I’ll always try to do my best, ”said the Dutchman. “It will be an exciting end to the season,” said the 24-year-old.

Preview of Formula 1 duel in Jeddah

The penultimate Formula 1 Grand Prix in Jeddah at the weekend will again deliver a duel between Max Verstappen and Lewis Hamilton.

More exciting than it has been for a long time

Ralf Schumacher is hoping for a sporty, fair decision in the exciting World Cup in 2021. “This is a mega season. One of the most exciting in a long time. It would be a shame if the FIA ​​(the international automobile association, note) had to decide who will be world champion, ”said the former Formula 1 driver and brother of record world champion Michael Schumacher. Ex-F1 driver Christian Klien agreed. “We only experienced verbal taunts between the teams, not between the drivers. They behave professionally and do their job. “

Verstappen holt Title with …

  • Victory plus extra point, Hamilton a maximum of sixth
  • Victory without extra point, Hamilton maximum seventh
  • Second place plus extra point, Hamilton a maximum of tenth
  • Second place without extra point, Hamilton without points

With his eighth title win, Hamilton could put himself at the top of the all-time ranking, ahead of Michael Schumacher, and continue as the sole record world champion. “Lewis is running out of time and nobody knows how the car will go next year,” said Schumacher and advises that it be better to clinch the eighth title this year. In his opinion, Hamilton therefore has more to lose. “The pressure is more on Lewis. And it is difficult to estimate how much support he will get from Valtteri Bottas. “

Hamilton can’t go all out

Red Bull, on the other hand, is building on four cars, after Sergio Perez and the drivers of the second Mateschitz team, Alpha Tauri Verstappen, are unlikely to get in the way. Schumacher is convinced that if there is a risk of collision, Hamilton will rather withdraw, as he did in Brazil. “Lewis has to be very careful. Because if it crashes, Max could take it. I hope not, but now it’s all about. “

According to the German, drivers and teams are nervous. “But it is nice to see that it goes to the last race.” Without his – partly through no fault of his – failures, Verstappen would have long been world champion, said Schumacher. Going back five places on the starting grid with an engine change and having a powerful engine like Mercedes in the last race in Abu Dhabi is definitely an option. But it’s not just about the engine. “Mercedes has been better lately, especially when it comes to handling the tires.”

He would like to spare himself and the spectators further objections from the two teams fighting for the title, said Schumacher. “It would be a shame to have this exciting duel.” In the past, Bernie Ecclestone had a different approach. “He came in to us and said that whoever interferes won’t get a super license next year.” A title duel is tough, but it has to be fair. “You have to be able to look each other in the eye. That should work this time too, the two of them will work it out between themselves. “

We wish to thank the writer of this post for this awesome web content

Formula 1: Mercedes promises “grenade” for the final spurt

" ["date_timestamp"]=> int(1638527676) } [4]=> array(11) { ["title"]=> string(83) "Under 21 World Cup, Velasco: “Humble and hardworking, it’s everyone’s gold”" ["link"]=> string(99) "https://moustachebrothers.com/under-21-world-cup-velasco-humble-and-hardworking-its-everyones-gold/" ["dc"]=> array(1) { ["creator"]=> string(12) "Sally Scully" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 10:13:45 +0000" ["category"]=> string(50) "VolleyBallCupeveryonesgoldhardworkingHumbleVelasco" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8795" ["description"]=> string(684) "Julio was a coach 30 years ago and a dt today: a close link between the two teams’ victories in the Junior World Cup Gian Luca Pasini October 5th – Milano Thirty years later. History repeats itself. Then Julio Velasco had brought Italian volleyball to the top class by focusing on a group of young ... Read more" ["content"]=> array(1) { ["encoded"]=> string(6491) "

Julio was a coach 30 years ago and a dt today: a close link between the two teams’ victories in the Junior World Cup

Gian Luca Pasini

Thirty years later. History repeats itself. Then Julio Velasco had brought Italian volleyball to the top class by focusing on a group of young people who came out of a project (Volley 85, wanted by Gianfranco Briani) which was based on the National jr, silver at the Milan World Cup, with the various Zorzi, Gardini, Tofoli, Cantagalli. Today Velasco is the director of a movement that, for the first time won the Junior World Cup (this time in Cagliari) and which strengthens the Italian image immediately after the European Championship won with Fefé De Giorgi on the bench.

Let’s start with the emotions, not much has been seen in the photos …

“As we get older we are moved more easily. But the victory in Cagliari was very intense. Also for the relationships built in the team, with the boys. The photos? It was right that Angiolino Frigoni was the coach.”

A great success though?

“I don’t think it’s just the victory of the team, but of the whole Italian movement. And I say this with sincerity. If it hadn’t been for that first coach who brought Catania or Michieletto to the gym, if it hadn’t been for that first club that made them play, today we would not have the team we have. When we teach players that team play is fundamental we must also practice it at an adult level. This gold is a gold of all Italian volleyball, not to say, in the facts”.

Did you use the same words with these guys that you used with the historical group?

“The times are different, it is certain, the conditions are very different, but some things are the same. This is why in recent years I have asked some of those players (Bernardi, Gardini) to speak to the team. De Giorgi was very good at communicate to his group some fundamental points of the program that were based on pivotal points “.

What did he say to the boys before the final?

“Some things are not said outside, they remain in the locker room”.

Tell us at least the general points.

“That from today begins a confrontation between these guys in the clubs and foreigners. There will be nothing to do with welfare assistance, nor the compliments received. Every day in the gym they will have to prove that they are better than the foreigners who come here with another idea. Playing in Italy for them is not having a starting place or not, but the difference is playing another chance at life. Now if you ask me if the Italian boys are ready to win this challenge, I say yes. They are. “

Can you draw a parallel between the two groups?

“No, impossible even in light of how the whole context has changed. But I say that this team has everything to get there, on the condition that it wants to continue learning. It seems to me that it wants to do so. I don’t believe in single thought (technically) , I’m fine with the discussion. What you must not miss is to work (a lot), even more than others, you must not become self-referential or presumptuous. The enemy of these victories is to lose humility. I do not think there was a secret of that Italy in the 90s, but looking back at those times and comparing them with today I say that the real difference lies in the trust. The players need to feel that the coach believes in them. Really, not just to put it: I strongly believed in that group, as I believe in this today. “

You don’t like talking about singles, but what if you think back to Michieletto’s summer?

“What more could you want? Nothing. But I like to remember how it was when he arrived. He was a captain and of course he found Rinaldi in his place. Ale didn’t demand anything, I saw him bring ice for everyone. No privileges. He and his family have a lot to do with this. “

Is the future blue then?

“There are all the conditions to answer yes. But beware of the demons that are underground. Ready to re-emerge: humility, work and desire to learn”.

We have seen that the Italian movement is capable of producing talents.

“I would do a division. The female has problems of abundance similar to football. For the male the problem is still recruitment. I have a couple of ideas to throw at the federal council: let’s go find the children of the less well-off people. There are important numbers. and even more interesting prospects “.

We would love to give thanks to the writer of this article for this outstanding material

Under 21 World Cup, Velasco: “Humble and hardworking, it’s everyone’s gold”

" } ["summary"]=> string(684) "Julio was a coach 30 years ago and a dt today: a close link between the two teams’ victories in the Junior World Cup Gian Luca Pasini October 5th – Milano Thirty years later. History repeats itself. Then Julio Velasco had brought Italian volleyball to the top class by focusing on a group of young ... Read more" ["atom_content"]=> string(6491) "

Julio was a coach 30 years ago and a dt today: a close link between the two teams’ victories in the Junior World Cup

Gian Luca Pasini

Thirty years later. History repeats itself. Then Julio Velasco had brought Italian volleyball to the top class by focusing on a group of young people who came out of a project (Volley 85, wanted by Gianfranco Briani) which was based on the National jr, silver at the Milan World Cup, with the various Zorzi, Gardini, Tofoli, Cantagalli. Today Velasco is the director of a movement that, for the first time won the Junior World Cup (this time in Cagliari) and which strengthens the Italian image immediately after the European Championship won with Fefé De Giorgi on the bench.

Let’s start with the emotions, not much has been seen in the photos …

“As we get older we are moved more easily. But the victory in Cagliari was very intense. Also for the relationships built in the team, with the boys. The photos? It was right that Angiolino Frigoni was the coach.”

A great success though?

“I don’t think it’s just the victory of the team, but of the whole Italian movement. And I say this with sincerity. If it hadn’t been for that first coach who brought Catania or Michieletto to the gym, if it hadn’t been for that first club that made them play, today we would not have the team we have. When we teach players that team play is fundamental we must also practice it at an adult level. This gold is a gold of all Italian volleyball, not to say, in the facts”.

Did you use the same words with these guys that you used with the historical group?

“The times are different, it is certain, the conditions are very different, but some things are the same. This is why in recent years I have asked some of those players (Bernardi, Gardini) to speak to the team. De Giorgi was very good at communicate to his group some fundamental points of the program that were based on pivotal points “.

What did he say to the boys before the final?

“Some things are not said outside, they remain in the locker room”.

Tell us at least the general points.

“That from today begins a confrontation between these guys in the clubs and foreigners. There will be nothing to do with welfare assistance, nor the compliments received. Every day in the gym they will have to prove that they are better than the foreigners who come here with another idea. Playing in Italy for them is not having a starting place or not, but the difference is playing another chance at life. Now if you ask me if the Italian boys are ready to win this challenge, I say yes. They are. “

Can you draw a parallel between the two groups?

“No, impossible even in light of how the whole context has changed. But I say that this team has everything to get there, on the condition that it wants to continue learning. It seems to me that it wants to do so. I don’t believe in single thought (technically) , I’m fine with the discussion. What you must not miss is to work (a lot), even more than others, you must not become self-referential or presumptuous. The enemy of these victories is to lose humility. I do not think there was a secret of that Italy in the 90s, but looking back at those times and comparing them with today I say that the real difference lies in the trust. The players need to feel that the coach believes in them. Really, not just to put it: I strongly believed in that group, as I believe in this today. “

You don’t like talking about singles, but what if you think back to Michieletto’s summer?

“What more could you want? Nothing. But I like to remember how it was when he arrived. He was a captain and of course he found Rinaldi in his place. Ale didn’t demand anything, I saw him bring ice for everyone. No privileges. He and his family have a lot to do with this. “

Is the future blue then?

“There are all the conditions to answer yes. But beware of the demons that are underground. Ready to re-emerge: humility, work and desire to learn”.

We have seen that the Italian movement is capable of producing talents.

“I would do a division. The female has problems of abundance similar to football. For the male the problem is still recruitment. I have a couple of ideas to throw at the federal council: let’s go find the children of the less well-off people. There are important numbers. and even more interesting prospects “.

We would love to give thanks to the writer of this article for this outstanding material

Under 21 World Cup, Velasco: “Humble and hardworking, it’s everyone’s gold”

" ["date_timestamp"]=> int(1638526425) } [5]=> array(11) { ["title"]=> string(72) "In children with multiple sclerosis, teriflunomide tempers lesion growth" ["link"]=> string(102) "https://moustachebrothers.com/in-children-with-multiple-sclerosis-teriflunomide-tempers-lesion-growth/" ["dc"]=> array(1) { ["creator"]=> string(12) "Tony Grantly" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 10:11:25 +0000" ["category"]=> string(75) "Health And Sciencechildrengrowthlesionmultiplesclerosistempersteriflunomide" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8790" ["description"]=> string(739) "Journal Reference: Tanuja Chitnis, Brenda Banwell, Ludwig Kappos, Douglas L Arnold, Kivilcim Gücüyener, Kumaran Deiva, Natalia Skripchenko, Li-Ying Cui, Stephane Saubadu, Wenruo Hu, Myriam Benamor, Annaig Le-Halpere, Philippe Truffinet, Marc Tardieu, Benedicte Dubois, Helene Verhelst, Veneta Bojinova-Tchamova, Jean Mah, Li-Ying Cui, Fang Fang, Yunpeng Hao, Li Jiang, Ling Li, Ding’An Mao, Wei Qiu, Guojun Tan, ... Read more" ["content"]=> array(1) { ["encoded"]=> string(4755) "

Journal Reference:

  1. Tanuja Chitnis, Brenda Banwell, Ludwig Kappos, Douglas L Arnold, Kivilcim Gücüyener, Kumaran Deiva, Natalia Skripchenko, Li-Ying Cui, Stephane Saubadu, Wenruo Hu, Myriam Benamor, Annaig Le-Halpere, Philippe Truffinet, Marc Tardieu, Benedicte Dubois, Helene Verhelst, Veneta Bojinova-Tchamova, Jean Mah, Li-Ying Cui, Fang Fang, Yunpeng Hao, Li Jiang, Ling Li, Ding’An Mao, Wei Qiu, Guojun Tan, Ye Wu, Meini Zhang, Hongyu Zhou, Shuizhen Zhou, Katrin Gross-Paju, Emmanuel Cheuret, Kumaran Deiva, Giles Edan, Sandra Vukusic, George Chrousos, Dimitrios Zafeiriou, Anat Achiron, Adi Vaknin-Dembinsky, Bassem Yamout, Jurate Laurynaitiene, Nerija Vaiciene-Magistris, Vladimir Bojkovski, Vesna Trajkova, Sana Chaouki, Najib Kissani, Rinze Neuteboom, Filipe Palavra, Anna Belova, Alexey Boyko, Evgeny Evdoshenko, Ekaterina Kairbekova, Nadezhda Malkova, Maria Shumilina, Natalya Skripchenko, Dimitrije Nikolic, Jose Meca-Lallana, Chahnez Charfi Triki, Mhiri Chokri, Riadh Gouider, Banu Anlar, Kivilcim Gücüyener, Ayse Semra Hiz, Egemen Idiman, Recai Turkoglu, Zuhal Yapici, Unsal Yilmaz, Lyudmyla Tantsura, Nataliia Voloshyna, Ming Lim, Evangeline Wassmer, Mark Cascione, Tanuja Chitnis, Christopher LaGanke, Kevin Rathke, John Scagnelli. Safety and efficacy of teriflunomide in paediatric multiple sclerosis (TERIKIDS): a multicentre, double-blind, phase 3, randomised, placebo-controlled trial. The Lancet Neurology, 2021; 20 (12): 1001 DOI: 10.1016/S1474-4422(21)00364-1

In the trial, called TERIKIDS, 109 children were randomized to receive teriflunomide and 57 were randomized to receive placebo for up to 96 weeks (nearly two years). Early entry in an open-label extension phase (where patients were guaranteed to receive teriflunomide) was possible before the end of the double-blind period for patients who experienced a relapse or demonstrated high disease activity on MRI imaging tests.Importantly, more patients in the placebo group entered the open-label extension phase (because of high MRI activity) than anticipated, with 26% of patients switching from placebo to teriflunomide before 96 weeks.

After 96 weeks, there was no difference in time to first clinical relapse of multiple sclerosis with teriflunomide compared with placebo. Teriflunomide was well tolerated — serious adverse events occurred in 11% of patients in the teriflunomide group and 11% of patients in the placebo group. Nasal inflammation, upper-respiratory-tract infection, hair loss, tingling sensations, abdominal pain, and increased blood creatine phosphokinase (a marker of muscle damage) were more frequent with teriflunomide than with placebo.

“The trial did not meet its primary endpoint — delaying time to the next clinical relapse — possibly because of more frequent switches to the open-label arm due to high MRI activity. However, the study did meet several key secondary endpoints related to teriflunomide’s ability to reduce the number of new or enlarged lesions that are detected through MRI, suggesting that the medication might have beneficial effects in children with relapsing forms of multiple sclerosis,” says lead author Tanuja Chitnis, MD, director of the MGB Pediatric Multiple Sclerosis Center at MGH.

Chitnis notes that an ongoing open-label treatment extension study is continuing to evaluate the long-term effects of teriflunomide in young patients.

Chitnis is also director of the Translational Neuroimmunology Research Center at Brigham and Women’s Hospital and a professor of neurology at Harvard Medical School.

This work was supported by Sanofi.

We would like to say thanks to the writer of this short article for this amazing material

In children with multiple sclerosis, teriflunomide tempers lesion growth

" } ["summary"]=> string(739) "Journal Reference: Tanuja Chitnis, Brenda Banwell, Ludwig Kappos, Douglas L Arnold, Kivilcim Gücüyener, Kumaran Deiva, Natalia Skripchenko, Li-Ying Cui, Stephane Saubadu, Wenruo Hu, Myriam Benamor, Annaig Le-Halpere, Philippe Truffinet, Marc Tardieu, Benedicte Dubois, Helene Verhelst, Veneta Bojinova-Tchamova, Jean Mah, Li-Ying Cui, Fang Fang, Yunpeng Hao, Li Jiang, Ling Li, Ding’An Mao, Wei Qiu, Guojun Tan, ... Read more" ["atom_content"]=> string(4755) "

Journal Reference:

  1. Tanuja Chitnis, Brenda Banwell, Ludwig Kappos, Douglas L Arnold, Kivilcim Gücüyener, Kumaran Deiva, Natalia Skripchenko, Li-Ying Cui, Stephane Saubadu, Wenruo Hu, Myriam Benamor, Annaig Le-Halpere, Philippe Truffinet, Marc Tardieu, Benedicte Dubois, Helene Verhelst, Veneta Bojinova-Tchamova, Jean Mah, Li-Ying Cui, Fang Fang, Yunpeng Hao, Li Jiang, Ling Li, Ding’An Mao, Wei Qiu, Guojun Tan, Ye Wu, Meini Zhang, Hongyu Zhou, Shuizhen Zhou, Katrin Gross-Paju, Emmanuel Cheuret, Kumaran Deiva, Giles Edan, Sandra Vukusic, George Chrousos, Dimitrios Zafeiriou, Anat Achiron, Adi Vaknin-Dembinsky, Bassem Yamout, Jurate Laurynaitiene, Nerija Vaiciene-Magistris, Vladimir Bojkovski, Vesna Trajkova, Sana Chaouki, Najib Kissani, Rinze Neuteboom, Filipe Palavra, Anna Belova, Alexey Boyko, Evgeny Evdoshenko, Ekaterina Kairbekova, Nadezhda Malkova, Maria Shumilina, Natalya Skripchenko, Dimitrije Nikolic, Jose Meca-Lallana, Chahnez Charfi Triki, Mhiri Chokri, Riadh Gouider, Banu Anlar, Kivilcim Gücüyener, Ayse Semra Hiz, Egemen Idiman, Recai Turkoglu, Zuhal Yapici, Unsal Yilmaz, Lyudmyla Tantsura, Nataliia Voloshyna, Ming Lim, Evangeline Wassmer, Mark Cascione, Tanuja Chitnis, Christopher LaGanke, Kevin Rathke, John Scagnelli. Safety and efficacy of teriflunomide in paediatric multiple sclerosis (TERIKIDS): a multicentre, double-blind, phase 3, randomised, placebo-controlled trial. The Lancet Neurology, 2021; 20 (12): 1001 DOI: 10.1016/S1474-4422(21)00364-1

In the trial, called TERIKIDS, 109 children were randomized to receive teriflunomide and 57 were randomized to receive placebo for up to 96 weeks (nearly two years). Early entry in an open-label extension phase (where patients were guaranteed to receive teriflunomide) was possible before the end of the double-blind period for patients who experienced a relapse or demonstrated high disease activity on MRI imaging tests.Importantly, more patients in the placebo group entered the open-label extension phase (because of high MRI activity) than anticipated, with 26% of patients switching from placebo to teriflunomide before 96 weeks.

After 96 weeks, there was no difference in time to first clinical relapse of multiple sclerosis with teriflunomide compared with placebo. Teriflunomide was well tolerated — serious adverse events occurred in 11% of patients in the teriflunomide group and 11% of patients in the placebo group. Nasal inflammation, upper-respiratory-tract infection, hair loss, tingling sensations, abdominal pain, and increased blood creatine phosphokinase (a marker of muscle damage) were more frequent with teriflunomide than with placebo.

“The trial did not meet its primary endpoint — delaying time to the next clinical relapse — possibly because of more frequent switches to the open-label arm due to high MRI activity. However, the study did meet several key secondary endpoints related to teriflunomide’s ability to reduce the number of new or enlarged lesions that are detected through MRI, suggesting that the medication might have beneficial effects in children with relapsing forms of multiple sclerosis,” says lead author Tanuja Chitnis, MD, director of the MGB Pediatric Multiple Sclerosis Center at MGH.

Chitnis notes that an ongoing open-label treatment extension study is continuing to evaluate the long-term effects of teriflunomide in young patients.

Chitnis is also director of the Translational Neuroimmunology Research Center at Brigham and Women’s Hospital and a professor of neurology at Harvard Medical School.

This work was supported by Sanofi.

We would like to say thanks to the writer of this short article for this amazing material

In children with multiple sclerosis, teriflunomide tempers lesion growth

" ["date_timestamp"]=> int(1638526285) } [6]=> array(11) { ["title"]=> string(35) "Quantum computers getting connected" ["link"]=> string(66) "https://moustachebrothers.com/quantum-computers-getting-connected/" ["dc"]=> array(1) { ["creator"]=> string(12) "Tony Grantly" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 08:54:25 +0000" ["category"]=> string(43) "Health And Sciencecomputersconnectedquantum" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8785" ["description"]=> string(650) "Journal Reference: Charles Babin, Rainer Stöhr, Naoya Morioka, Tobias Linkewitz, Timo Steidl, Raphael Wörnle, Di Liu, Erik Hesselmeier, Vadim Vorobyov, Andrej Denisenko, Mario Hentschel, Christian Gobert, Patrick Berwian, Georgy V. Astakhov, Wolfgang Knolle, Sridhar Majety, Pranta Saha, Marina Radulaski, Nguyen Tien Son, Jawad Ul-Hassan, Florian Kaiser, Jörg Wrachtrup. Fabrication and nanophotonic waveguide integration of silicon ... Read more" ["content"]=> array(1) { ["encoded"]=> string(4741) "

Journal Reference:

  1. Charles Babin, Rainer Stöhr, Naoya Morioka, Tobias Linkewitz, Timo Steidl, Raphael Wörnle, Di Liu, Erik Hesselmeier, Vadim Vorobyov, Andrej Denisenko, Mario Hentschel, Christian Gobert, Patrick Berwian, Georgy V. Astakhov, Wolfgang Knolle, Sridhar Majety, Pranta Saha, Marina Radulaski, Nguyen Tien Son, Jawad Ul-Hassan, Florian Kaiser, Jörg Wrachtrup. Fabrication and nanophotonic waveguide integration of silicon carbide colour centres with preserved spin-optical coherence. Nature Materials, 2021; DOI: 10.1038/s41563-021-01148-3

One of the main obstacles towards the commercialization of quantum photonics remains the nanoscale fabrication and integration of scalable quantum systems due to their notorious sensitivity to the smallest disturbances in the close environment. This has made it an extraordinary challenge to develop systems that can be used for quantum computing while simultaneously offering an efficient optical interface.

A recent result published in Nature Materials shows how the integration obstacle can be overcome. The work is based on a multi-national collaboration with researchers from Universities of Stuttgart (Physics 3), California — Davis, Linköping and Kyoto, as well as the Fraunhofer Institute at Erlangen, the Helmholtz Centre at Dresden and the Leibniz-Institute at Leipzig.

The researchers followed a two-step approach. First, their quantum system of choice is the so-called silicon vacancy centre in silicon carbide, which is known to possess particularly robust spin-optical properties. Second, they fabricated nanophotonic waveguides around these colour centres using gentle processing methods that keep the host material essentially free of damage.

“With our approach, we could demonstrate that the excellent spin-optical properties of our colour centres are maintained after nanophotonic integration.” says Florian Kaiser, Assistant Professor at the University of Stuttgart, the supervisor of this project. “Thanks to the robustness of our quantum devices, we gained enough headroom to perform quantum gates on multiple nuclear spin qubits. As these spins show very long coherence times, they are excellent for implementing small quantum computers.”

“In this project, we explored the peculiar triangular shape of photonic devices. While this geometry is of commercial appeal because it provides versatility needed for scalable production, little has been known about its utility for high performing quantum hardware. Our studies reveal that light emitted by the colour centre, which carries quantum information across the chip, can be efficiently propagated through a single optical mode. This is a key conclusion for viability of integration of colour centres with other photonic devices, such as nanocavities, optical fibre and single-photon detectors, needed to realize full functionalities of quantum networking and computing.” — says Marina Radulaski, Assistant Professor at the University of California — Davis.

What makes the silicon carbide platform particularly interesting are its CMOS compatibility and its heavy usage as high-power semiconductor in electric mobility. The researchers now want to benefit from these aspects to leverage the scalable production of spin-photonics chips. Additionally, they want to implement semiconductor circuitry to electrically initialise and readout the quantum states of their spin qubits. “Maximising electrical control — instead of traditional optical control via lasers — is an important step towards system simplification. The combination of efficient nanophotonics with electrical control will allow us to reliably integrate more quantum systems on one chip, which will result in significant performance gains.,” adds Florian Kaiser, “In this sense, we are only at the dawn of quantum technologies with colour centres in silicon carbide. Our successful nanophotonic integration is not only an exciting enabler for distributed quantum computing, but it can also boost the performance of compact quantum sensors.”

We would like to say thanks to the author of this write-up for this awesome content

Quantum computers getting connected

" } ["summary"]=> string(650) "Journal Reference: Charles Babin, Rainer Stöhr, Naoya Morioka, Tobias Linkewitz, Timo Steidl, Raphael Wörnle, Di Liu, Erik Hesselmeier, Vadim Vorobyov, Andrej Denisenko, Mario Hentschel, Christian Gobert, Patrick Berwian, Georgy V. Astakhov, Wolfgang Knolle, Sridhar Majety, Pranta Saha, Marina Radulaski, Nguyen Tien Son, Jawad Ul-Hassan, Florian Kaiser, Jörg Wrachtrup. Fabrication and nanophotonic waveguide integration of silicon ... Read more" ["atom_content"]=> string(4741) "

Journal Reference:

  1. Charles Babin, Rainer Stöhr, Naoya Morioka, Tobias Linkewitz, Timo Steidl, Raphael Wörnle, Di Liu, Erik Hesselmeier, Vadim Vorobyov, Andrej Denisenko, Mario Hentschel, Christian Gobert, Patrick Berwian, Georgy V. Astakhov, Wolfgang Knolle, Sridhar Majety, Pranta Saha, Marina Radulaski, Nguyen Tien Son, Jawad Ul-Hassan, Florian Kaiser, Jörg Wrachtrup. Fabrication and nanophotonic waveguide integration of silicon carbide colour centres with preserved spin-optical coherence. Nature Materials, 2021; DOI: 10.1038/s41563-021-01148-3

One of the main obstacles towards the commercialization of quantum photonics remains the nanoscale fabrication and integration of scalable quantum systems due to their notorious sensitivity to the smallest disturbances in the close environment. This has made it an extraordinary challenge to develop systems that can be used for quantum computing while simultaneously offering an efficient optical interface.

A recent result published in Nature Materials shows how the integration obstacle can be overcome. The work is based on a multi-national collaboration with researchers from Universities of Stuttgart (Physics 3), California — Davis, Linköping and Kyoto, as well as the Fraunhofer Institute at Erlangen, the Helmholtz Centre at Dresden and the Leibniz-Institute at Leipzig.

The researchers followed a two-step approach. First, their quantum system of choice is the so-called silicon vacancy centre in silicon carbide, which is known to possess particularly robust spin-optical properties. Second, they fabricated nanophotonic waveguides around these colour centres using gentle processing methods that keep the host material essentially free of damage.

“With our approach, we could demonstrate that the excellent spin-optical properties of our colour centres are maintained after nanophotonic integration.” says Florian Kaiser, Assistant Professor at the University of Stuttgart, the supervisor of this project. “Thanks to the robustness of our quantum devices, we gained enough headroom to perform quantum gates on multiple nuclear spin qubits. As these spins show very long coherence times, they are excellent for implementing small quantum computers.”

“In this project, we explored the peculiar triangular shape of photonic devices. While this geometry is of commercial appeal because it provides versatility needed for scalable production, little has been known about its utility for high performing quantum hardware. Our studies reveal that light emitted by the colour centre, which carries quantum information across the chip, can be efficiently propagated through a single optical mode. This is a key conclusion for viability of integration of colour centres with other photonic devices, such as nanocavities, optical fibre and single-photon detectors, needed to realize full functionalities of quantum networking and computing.” — says Marina Radulaski, Assistant Professor at the University of California — Davis.

What makes the silicon carbide platform particularly interesting are its CMOS compatibility and its heavy usage as high-power semiconductor in electric mobility. The researchers now want to benefit from these aspects to leverage the scalable production of spin-photonics chips. Additionally, they want to implement semiconductor circuitry to electrically initialise and readout the quantum states of their spin qubits. “Maximising electrical control — instead of traditional optical control via lasers — is an important step towards system simplification. The combination of efficient nanophotonics with electrical control will allow us to reliably integrate more quantum systems on one chip, which will result in significant performance gains.,” adds Florian Kaiser, “In this sense, we are only at the dawn of quantum technologies with colour centres in silicon carbide. Our successful nanophotonic integration is not only an exciting enabler for distributed quantum computing, but it can also boost the performance of compact quantum sensors.”

We would like to say thanks to the author of this write-up for this awesome content

Quantum computers getting connected

" ["date_timestamp"]=> int(1638521665) } [7]=> array(11) { ["title"]=> string(87) "Horner-Wolff, ferocious jokes and complaints: the world championship gets into the ring" ["link"]=> string(116) "https://moustachebrothers.com/horner-wolff-ferocious-jokes-and-complaints-the-world-championship-gets-into-the-ring/" ["dc"]=> array(1) { ["creator"]=> string(11) "David Lonit" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 08:26:27 +0000" ["category"]=> string(56) "Formula 1championshipcomplaintsFerociousHornerWolffjokes" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8779" ["description"]=> string(680) "The Englishman, a former driver, is one of the authors of the Red Bull miracle: 4 titles in a row with Vettel; the Austrian is a self-made financier. What a fight this year The challenge to the sound of accusations and low blows between Christian Horner and Toto Wolff animated the 2021 World Championship almost ... Read more" ["content"]=> array(1) { ["encoded"]=> string(6496) "

The Englishman, a former driver, is one of the authors of the Red Bull miracle: 4 titles in a row with Vettel; the Austrian is a self-made financier. What a fight this year

The challenge to the sound of accusations and low blows between Christian Horner and Toto Wolff animated the 2021 World Championship almost as much as the duel on the track between their pupils Max Verstappen and Lewis Hamilton. Never the level of the clash between team principals had reached certain peaks, turning the spotlight on the men who manage the battleships Red Bull-Honda and Mercedes. The aplomb vanished very soon and the two did not miss an opportunity to exchange long-distance polemical responses and poison phrases throughout the championship. Horner and Wolff did not miss anything, sometimes going well beyond “fair play”. From the first race, in Bahrain, up to the twentieth, in Qatar, all sorts of things were said. Phrases like these: “Christian is a big balloon who loves to make himself beautiful in front of the cameras. We should be more modest”. Or: “I respect what Mercedes and Hamilton did, but I don’t have to go to dinner with Toto and I don’t need to kiss his c..o! Understand the climate?

On the other hand, this season has turned into an all-out war, on and off the track, which is fought with every weapon, including communication. It is part of the F1 game, where everyone tries to destabilize the enemy and weaken him, using strategy as in a game of Risk. The political battle between Wolff and Horner, or between Mercedes and Red Bull-Honda, has been incessant, with suspicions on both sides, requests for technical clarifications from the FIA ​​and sporting complaints for the drivers’ maneuvers. Red Bull, queen of the winter tests, took the lead in the first part of the championship because the genius Adrian Newey was able to better adapt the chassis and aerodynamics to the small (but decisive) regulatory changes imposed at the beginning of 2021. So then here is Wolff’s first move, in Baku, when Mercedes calls for stricter controls on the flexibility of the rear wing of Red Bull, which will come into effect from France. Horner retorts: “Our car passed the tests, so it’s legal, if I were in Toto I’d shut up looking at their front wing …”. Then Horner goes on the counterattack with an official complaint after the Silverstone incident, in which Hamilton rams Verstappen at 290 per hour and sends him against the barriers, considering the 10 “penalty too light that allowed Lewis to win the race (the appeal was rejected). We arrive in Brazil and Hamilton’s Mercedes is relegated to last position after qualifying due to the excessive opening of the moving wing (Drs) on the straight, an episode that does not prevent Lewis from recovering in the “sprint race” on Saturday and then back in the race, taking an incredible triumph. The spied on the commissioners, of course, had been from Red Bull … So another complaint, this time from Wolff, to punish Verstappen, who at 48th lap had defended himself from an overtaking by Hamilton taking his rival off the track without receiving the 5 “penalty (the appeal is still rejected). While Horner throws new suspicions on the power unit mounted by Lewis at Interlagos. Who knows if they have other surprises in store for the last 2 GPs in Jeddah and Abu Dhabi.

According to Horner, Wolff’s attacks are a sign of nervousness: “This is the first time anyone has put pressure on them, because Mercedes had never had any rivals in the era of hybrid engines, and it’s interesting to see how they are reacting.” In reality, the Red Bull boss is also agitated, judging by how he offended the commissioner who waved the yellow flag costing Verstappen the penalty in qualifying in Qatar, only to apologize and be fined. “It is a fierce fight between two great teams – observes Wolff -. We started with boxing and now we are in mixed martial arts, by now in the ring we have taken off our gloves”.

Born fighters

Toto is a fighter. He learned to fight when he was a little boy and lost his father. One day the principal of his private school came into the classroom and told everyone in front of everyone that he and his sister had to leave, because the mother could no longer pay their tuition. He became a finance guru, creating the most important “hi tech” fund in Austria, and then breaking through in New York. He joined F1 as a Williams shareholder, after being an amateur driver, and came to own 30% of Mercedes F1, a team worth one billion euros. Do you think a leader with Wolff’s strength, charisma and political weight could be frightened by a great challenge? His opponent Horner, cover character for his marriage to singer Geri Halliwell ex Spice Girls, is no less in terms of character and political ability. A former Formula 3000 driver, he was one of the architects of the Red Bull miracle, leading the team from nothing to the four world championship triumphs achieved in the Vettel era. It also helped lay the foundations for the future, with the creation of an engine department in Milton Keynes from which home-built power units will be released in 2025-26. Horner has moved in an unscrupulous way on the market, snatching specialized engineers from Mercedes. Another reason Wolff swore revenge on him.

We would love to give thanks to the author of this write-up for this remarkable web content

Horner-Wolff, ferocious jokes and complaints: the world championship gets into the ring

" } ["summary"]=> string(680) "The Englishman, a former driver, is one of the authors of the Red Bull miracle: 4 titles in a row with Vettel; the Austrian is a self-made financier. What a fight this year The challenge to the sound of accusations and low blows between Christian Horner and Toto Wolff animated the 2021 World Championship almost ... Read more" ["atom_content"]=> string(6496) "

The Englishman, a former driver, is one of the authors of the Red Bull miracle: 4 titles in a row with Vettel; the Austrian is a self-made financier. What a fight this year

The challenge to the sound of accusations and low blows between Christian Horner and Toto Wolff animated the 2021 World Championship almost as much as the duel on the track between their pupils Max Verstappen and Lewis Hamilton. Never the level of the clash between team principals had reached certain peaks, turning the spotlight on the men who manage the battleships Red Bull-Honda and Mercedes. The aplomb vanished very soon and the two did not miss an opportunity to exchange long-distance polemical responses and poison phrases throughout the championship. Horner and Wolff did not miss anything, sometimes going well beyond “fair play”. From the first race, in Bahrain, up to the twentieth, in Qatar, all sorts of things were said. Phrases like these: “Christian is a big balloon who loves to make himself beautiful in front of the cameras. We should be more modest”. Or: “I respect what Mercedes and Hamilton did, but I don’t have to go to dinner with Toto and I don’t need to kiss his c..o! Understand the climate?

On the other hand, this season has turned into an all-out war, on and off the track, which is fought with every weapon, including communication. It is part of the F1 game, where everyone tries to destabilize the enemy and weaken him, using strategy as in a game of Risk. The political battle between Wolff and Horner, or between Mercedes and Red Bull-Honda, has been incessant, with suspicions on both sides, requests for technical clarifications from the FIA ​​and sporting complaints for the drivers’ maneuvers. Red Bull, queen of the winter tests, took the lead in the first part of the championship because the genius Adrian Newey was able to better adapt the chassis and aerodynamics to the small (but decisive) regulatory changes imposed at the beginning of 2021. So then here is Wolff’s first move, in Baku, when Mercedes calls for stricter controls on the flexibility of the rear wing of Red Bull, which will come into effect from France. Horner retorts: “Our car passed the tests, so it’s legal, if I were in Toto I’d shut up looking at their front wing …”. Then Horner goes on the counterattack with an official complaint after the Silverstone incident, in which Hamilton rams Verstappen at 290 per hour and sends him against the barriers, considering the 10 “penalty too light that allowed Lewis to win the race (the appeal was rejected). We arrive in Brazil and Hamilton’s Mercedes is relegated to last position after qualifying due to the excessive opening of the moving wing (Drs) on the straight, an episode that does not prevent Lewis from recovering in the “sprint race” on Saturday and then back in the race, taking an incredible triumph. The spied on the commissioners, of course, had been from Red Bull … So another complaint, this time from Wolff, to punish Verstappen, who at 48th lap had defended himself from an overtaking by Hamilton taking his rival off the track without receiving the 5 “penalty (the appeal is still rejected). While Horner throws new suspicions on the power unit mounted by Lewis at Interlagos. Who knows if they have other surprises in store for the last 2 GPs in Jeddah and Abu Dhabi.

According to Horner, Wolff’s attacks are a sign of nervousness: “This is the first time anyone has put pressure on them, because Mercedes had never had any rivals in the era of hybrid engines, and it’s interesting to see how they are reacting.” In reality, the Red Bull boss is also agitated, judging by how he offended the commissioner who waved the yellow flag costing Verstappen the penalty in qualifying in Qatar, only to apologize and be fined. “It is a fierce fight between two great teams – observes Wolff -. We started with boxing and now we are in mixed martial arts, by now in the ring we have taken off our gloves”.

Born fighters

Toto is a fighter. He learned to fight when he was a little boy and lost his father. One day the principal of his private school came into the classroom and told everyone in front of everyone that he and his sister had to leave, because the mother could no longer pay their tuition. He became a finance guru, creating the most important “hi tech” fund in Austria, and then breaking through in New York. He joined F1 as a Williams shareholder, after being an amateur driver, and came to own 30% of Mercedes F1, a team worth one billion euros. Do you think a leader with Wolff’s strength, charisma and political weight could be frightened by a great challenge? His opponent Horner, cover character for his marriage to singer Geri Halliwell ex Spice Girls, is no less in terms of character and political ability. A former Formula 3000 driver, he was one of the architects of the Red Bull miracle, leading the team from nothing to the four world championship triumphs achieved in the Vettel era. It also helped lay the foundations for the future, with the creation of an engine department in Milton Keynes from which home-built power units will be released in 2025-26. Horner has moved in an unscrupulous way on the market, snatching specialized engineers from Mercedes. Another reason Wolff swore revenge on him.

We would love to give thanks to the author of this write-up for this remarkable web content

Horner-Wolff, ferocious jokes and complaints: the world championship gets into the ring

" ["date_timestamp"]=> int(1638519987) } [8]=> array(11) { ["title"]=> string(116) "Forghieri remembers Williams: “Pure man, born to fight. Rivals, but how many times have I invited him to dinner”" ["link"]=> string(137) "https://moustachebrothers.com/forghieri-remembers-williams-pure-man-born-to-fight-rivals-but-how-many-times-have-i-invited-him-to-dinner/" ["dc"]=> array(1) { ["creator"]=> string(11) "Eden Kently" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 08:22:48 +0000" ["category"]=> string(71) "MotoringborndinnerFightForghieriinvitedPureremembersRivalstimesWilliams" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8773" ["description"]=> string(804) "The historic Ferrari engineer in F1 talks about Sir Frank, who passed away on November 28: “The nicest opponent I’ve ever had. At the beginning he didn’t have much money available … “ Andrea Fanì December 3 – Milano In F1, Frank Williams and Mauro Forghieri were bitter rivals. And today, 50 years later, the ... Read more" ["content"]=> array(1) { ["encoded"]=> string(6226) "

The historic Ferrari engineer in F1 talks about Sir Frank, who passed away on November 28: “The nicest opponent I’ve ever had. At the beginning he didn’t have much money available … “

Andrea Fanì

In F1, Frank Williams and Mauro Forghieri were bitter rivals. And today, 50 years later, the legendary engineer “father” of many Ferrari single-seaters remembers the great Sir Frank, who passed away on November 28, 2021. “A pure man, born to fight. If I could, ”smiles Forghieri,“ I would have beaten him in every way, but he was the nicest rival I’ve ever had in Formula 1 ”.

Engineer, by Frank Williams the first thing that comes to your mind is?

Ride. “That we weren’t friends … He’s always been a great rival, mine as a Ferrari. But as much as it could be in the F1 World Championship, always very correct ”.

But when Williams entered F1, did you underestimate them?

“Well, you know, we were Ferrari, every time a new team entered the World Championship one always wondered where he would go, what he would do”.

What impression did he initially make?

“He imported engines from Italy to England, he struggled to make a business out of them. In general, at that time there was much less money and everyone in the small teams got by. Not that everyone went to the hotel or had who knows what means, you know? Today there is a little too much money in the World Cup, then no. Take it from the right side but many times we have tried to invite him to dinner. I mean, I wasn’t happy when he won but there was enormous mutual respect. Then there was that phrase from Ferrari … “.

Who called them “garage owners”?

“Yes, but Ferrari was the first to know that they weren’t ‘garage owners’, he used those expressions for political reasons, let’s put it this way, in reality he was the first to have enormous respect for the opponents who won. As a Ferrari, I fought rivals like Williams in every way. I would have beaten him in all possible ways, but he was a great opponent ”.

Was there something in common between Ferrari and Williams?

“Nooo, nothing, nothing. Two distant worlds. Enzo Ferrari was an industrialist, a man with an industrial vision. Frank never was, he was born to be a fighter, and it’s by fighting that he earned the respect of all of F1. He was a pure man, dedicated body and soul to that profession, to the profession of racing. Maybe it was more like ‘us’ addicts, I mean? To say, I had the Ferrari behind me but you do not imagine how many sacrifices we made in the work. How much struggle there was, how much spirit. Frank, even though he was the boss of his team, was closer to us. To tell you: once, since we needed a new clutch, something a bit special, but the company didn’t want to spend that money, we technicians and mechanics took a collection to buy it. Understood, the sacrifices I’m talking about? “.

And when Williams dropped in the last period what did you think?

“I have always followed him with the sympathy of that time. I couldn’t have had a different attitude, he was the nicest rival I’ve ever had ”.

Of course the relationships between you were different from, say, a Mercedes-Red Bull of today …

“Well … yes. A lot of money, believe me, a lot of money. We always try to contain everything in the philosophy of regard, but once rivalry was also human closeness. Today many more means to fight and much more distance ”.

How does it end between Hamilton and Verstappen?

“Max Verstappen is strong, a handsome driver who can put even the greatest players in difficulty. But Lewis Hamilton is the greatest driver of the modern era, in an absolute sense. A professional at the top both for what he can do with the means he has, and for the moral qualities he puts into what he does. Hamilton is superior ”.

We want to thank the author of this article for this incredible material

Forghieri remembers Williams: “Pure man, born to fight. Rivals, but how many times have I invited him to dinner”

" } ["summary"]=> string(804) "The historic Ferrari engineer in F1 talks about Sir Frank, who passed away on November 28: “The nicest opponent I’ve ever had. At the beginning he didn’t have much money available … “ Andrea Fanì December 3 – Milano In F1, Frank Williams and Mauro Forghieri were bitter rivals. And today, 50 years later, the ... Read more" ["atom_content"]=> string(6226) "

The historic Ferrari engineer in F1 talks about Sir Frank, who passed away on November 28: “The nicest opponent I’ve ever had. At the beginning he didn’t have much money available … “

Andrea Fanì

In F1, Frank Williams and Mauro Forghieri were bitter rivals. And today, 50 years later, the legendary engineer “father” of many Ferrari single-seaters remembers the great Sir Frank, who passed away on November 28, 2021. “A pure man, born to fight. If I could, ”smiles Forghieri,“ I would have beaten him in every way, but he was the nicest rival I’ve ever had in Formula 1 ”.

Engineer, by Frank Williams the first thing that comes to your mind is?

Ride. “That we weren’t friends … He’s always been a great rival, mine as a Ferrari. But as much as it could be in the F1 World Championship, always very correct ”.

But when Williams entered F1, did you underestimate them?

“Well, you know, we were Ferrari, every time a new team entered the World Championship one always wondered where he would go, what he would do”.

What impression did he initially make?

“He imported engines from Italy to England, he struggled to make a business out of them. In general, at that time there was much less money and everyone in the small teams got by. Not that everyone went to the hotel or had who knows what means, you know? Today there is a little too much money in the World Cup, then no. Take it from the right side but many times we have tried to invite him to dinner. I mean, I wasn’t happy when he won but there was enormous mutual respect. Then there was that phrase from Ferrari … “.

Who called them “garage owners”?

“Yes, but Ferrari was the first to know that they weren’t ‘garage owners’, he used those expressions for political reasons, let’s put it this way, in reality he was the first to have enormous respect for the opponents who won. As a Ferrari, I fought rivals like Williams in every way. I would have beaten him in all possible ways, but he was a great opponent ”.

Was there something in common between Ferrari and Williams?

“Nooo, nothing, nothing. Two distant worlds. Enzo Ferrari was an industrialist, a man with an industrial vision. Frank never was, he was born to be a fighter, and it’s by fighting that he earned the respect of all of F1. He was a pure man, dedicated body and soul to that profession, to the profession of racing. Maybe it was more like ‘us’ addicts, I mean? To say, I had the Ferrari behind me but you do not imagine how many sacrifices we made in the work. How much struggle there was, how much spirit. Frank, even though he was the boss of his team, was closer to us. To tell you: once, since we needed a new clutch, something a bit special, but the company didn’t want to spend that money, we technicians and mechanics took a collection to buy it. Understood, the sacrifices I’m talking about? “.

And when Williams dropped in the last period what did you think?

“I have always followed him with the sympathy of that time. I couldn’t have had a different attitude, he was the nicest rival I’ve ever had ”.

Of course the relationships between you were different from, say, a Mercedes-Red Bull of today …

“Well … yes. A lot of money, believe me, a lot of money. We always try to contain everything in the philosophy of regard, but once rivalry was also human closeness. Today many more means to fight and much more distance ”.

How does it end between Hamilton and Verstappen?

“Max Verstappen is strong, a handsome driver who can put even the greatest players in difficulty. But Lewis Hamilton is the greatest driver of the modern era, in an absolute sense. A professional at the top both for what he can do with the means he has, and for the moral qualities he puts into what he does. Hamilton is superior ”.

We want to thank the author of this article for this incredible material

Forghieri remembers Williams: “Pure man, born to fight. Rivals, but how many times have I invited him to dinner”

" ["date_timestamp"]=> int(1638519768) } [9]=> array(11) { ["title"]=> string(83) "Beads of glass in meteorites help scientists piece together how solar system formed" ["link"]=> string(114) "https://moustachebrothers.com/beads-of-glass-in-meteorites-help-scientists-piece-together-how-solar-system-formed/" ["dc"]=> array(1) { ["creator"]=> string(12) "Tony Grantly" } ["pubdate"]=> string(31) "Fri, 03 Dec 2021 07:37:06 +0000" ["category"]=> string(64) "Health And ScienceBeadsformedglassmeteoritespieceScientistssolar" ["guid"]=> string(37) "https://moustachebrothers.com/?p=8768" ["description"]=> string(731) "Journal Reference: Nicole X. Nie, Xin-Yang Chen, Timo Hopp, Justin Y. Hu, Zhe J. Zhang, Fang-Zhen Teng, Anat Shahar, Nicolas Dauphas. Imprint of chondrule formation on the K and Rb isotopic compositions of carbonaceous meteorites. Science Advances, 2021; 7 (49) DOI: 10.1126/sciadv.abl3929 Scientists with the University of Chicago have published an analysis laying out how ... Read more" ["content"]=> array(1) { ["encoded"]=> string(5661) "

Journal Reference:

  1. Nicole X. Nie, Xin-Yang Chen, Timo Hopp, Justin Y. Hu, Zhe J. Zhang, Fang-Zhen Teng, Anat Shahar, Nicolas Dauphas. Imprint of chondrule formation on the K and Rb isotopic compositions of carbonaceous meteorites. Science Advances, 2021; 7 (49) DOI: 10.1126/sciadv.abl3929

Scientists with the University of Chicago have published an analysis laying out how these beads, which are found in many meteorites, came to be — and what they can tell us about what happened in the early solar system.

“These are big questions,” said UChicago alum Nicole Xike Nie, PhD’19, a postdoctoral fellow at the Carnegie Institution for Science and first author of the study. “Meteorites are snapshots that can reveal the conditions this early dust experienced — which has implications for the evolution of both Earth and other planets.”

‘This question goes back 50 years’

The beads of glass inside these meteorites are called chondrules. Scientists think they are bits of rock left over from the debris that was floating around billions of years ago, which eventually coalesced into the planets we now know and love. These are immensely useful to scientists, who can get their hands on pieces of the original stuff that comprised the solar system — before the constant churn of volcanoes and tectonic plates of Earth changed all the rock we can find on the planet itself.

But what exactly caused the formation of these chondrules remains unclear.

“We have the same theories we had 50 years ago,” said study co-author and UChicago postdoctoral researcher Timo Hopp. “Even though there have been advances in many other areas, this one has been stubborn.”

Scientists can find clues about the early days of the solar system by looking at the types of a given element in a rock. Elements can come in several different forms, called isotopes, and the proportion in each rock varies according to what happened when that rock was born — how hot it was, whether it cooled slowly or was flash-frozen, what other elements were around to interact with it. From there, scientists can piece together a history of likely events.

To try and understand what had happened to the chondrules, Nie, Hopp and other scientists at the Dauphas Origins Lab at UChicago tried applying a unique angle to the isotopes.

First, Nie took extremely rigorous, precise measurements of the concentrations and isotopes of two elements that are depleted in meteorites, potassium and rubidium, which helped narrow down the possibilities of what could have happened in the early solar system.

From this information, the team pieced together what must have been happening as the chondrules formed. The elements would have been part of a clump of dust that got hot enough to melt, and then to vaporize. Then, as the material cooled, some of that vapor coalesced back into chondrules.

“We can also tell you how fast it cooled, because it was fast enough that not everything condensed,” said Nicolas Dauphas, Professor of Geophysical Sciences at UChicago. “That must mean the temperature was dropping at a rate of around 500 degrees Celsius per hour, which is really fast.”

Based on these constraints, scientists can theorize what kind of event would have been sudden and violent enough to cause this extreme heating and cooling. One scenario that fits would be massive shockwaves passing through the early nebula. “Large planetary bodies nearby can create shocks, which would have heated and then cooled the dust as it passed through,” Dauphas said.

Over the past half-century, people have proposed different scenarios to explain the formation of the chondrules — lightning, or collisions between rocks — but this new evidence tips the balance toward shockwaves as an explanation.

This explanation may be the key to understanding a persistent finding that has bedeviled scientists for decades, involving a category of elements that are “moderately volatile,” including potassium and rubidium. The Earth has less of these elements than scientists would expect, based on their general understanding of how the solar system formed. They knew the explanation could be traced to some complex chain of heating and cooling, but no one know the exact sequence. “It’s a huge question in the field of cosmochemistry.” said Dauphas.

Now, finally, the team is happy to have put a significant dent in the mystery.

“We know other processes happened — this is just one part of the story — but this really solves one step in the formation of planets,” said Hopp.

Nie agreed: “It’s really cool to be able to say quantitatively, this is what happened.”

Other co-authors on the paper were from the Carnegie Institution for Science and the University of Washington.

We would love to give thanks to the writer of this write-up for this amazing material

Beads of glass in meteorites help scientists piece together how solar system formed

" } ["summary"]=> string(731) "Journal Reference: Nicole X. Nie, Xin-Yang Chen, Timo Hopp, Justin Y. Hu, Zhe J. Zhang, Fang-Zhen Teng, Anat Shahar, Nicolas Dauphas. Imprint of chondrule formation on the K and Rb isotopic compositions of carbonaceous meteorites. Science Advances, 2021; 7 (49) DOI: 10.1126/sciadv.abl3929 Scientists with the University of Chicago have published an analysis laying out how ... Read more" ["atom_content"]=> string(5661) "

Journal Reference:

  1. Nicole X. Nie, Xin-Yang Chen, Timo Hopp, Justin Y. Hu, Zhe J. Zhang, Fang-Zhen Teng, Anat Shahar, Nicolas Dauphas. Imprint of chondrule formation on the K and Rb isotopic compositions of carbonaceous meteorites. Science Advances, 2021; 7 (49) DOI: 10.1126/sciadv.abl3929

Scientists with the University of Chicago have published an analysis laying out how these beads, which are found in many meteorites, came to be — and what they can tell us about what happened in the early solar system.

“These are big questions,” said UChicago alum Nicole Xike Nie, PhD’19, a postdoctoral fellow at the Carnegie Institution for Science and first author of the study. “Meteorites are snapshots that can reveal the conditions this early dust experienced — which has implications for the evolution of both Earth and other planets.”

‘This question goes back 50 years’

The beads of glass inside these meteorites are called chondrules. Scientists think they are bits of rock left over from the debris that was floating around billions of years ago, which eventually coalesced into the planets we now know and love. These are immensely useful to scientists, who can get their hands on pieces of the original stuff that comprised the solar system — before the constant churn of volcanoes and tectonic plates of Earth changed all the rock we can find on the planet itself.

But what exactly caused the formation of these chondrules remains unclear.

“We have the same theories we had 50 years ago,” said study co-author and UChicago postdoctoral researcher Timo Hopp. “Even though there have been advances in many other areas, this one has been stubborn.”

Scientists can find clues about the early days of the solar system by looking at the types of a given element in a rock. Elements can come in several different forms, called isotopes, and the proportion in each rock varies according to what happened when that rock was born — how hot it was, whether it cooled slowly or was flash-frozen, what other elements were around to interact with it. From there, scientists can piece together a history of likely events.

To try and understand what had happened to the chondrules, Nie, Hopp and other scientists at the Dauphas Origins Lab at UChicago tried applying a unique angle to the isotopes.

First, Nie took extremely rigorous, precise measurements of the concentrations and isotopes of two elements that are depleted in meteorites, potassium and rubidium, which helped narrow down the possibilities of what could have happened in the early solar system.

From this information, the team pieced together what must have been happening as the chondrules formed. The elements would have been part of a clump of dust that got hot enough to melt, and then to vaporize. Then, as the material cooled, some of that vapor coalesced back into chondrules.

“We can also tell you how fast it cooled, because it was fast enough that not everything condensed,” said Nicolas Dauphas, Professor of Geophysical Sciences at UChicago. “That must mean the temperature was dropping at a rate of around 500 degrees Celsius per hour, which is really fast.”

Based on these constraints, scientists can theorize what kind of event would have been sudden and violent enough to cause this extreme heating and cooling. One scenario that fits would be massive shockwaves passing through the early nebula. “Large planetary bodies nearby can create shocks, which would have heated and then cooled the dust as it passed through,” Dauphas said.

Over the past half-century, people have proposed different scenarios to explain the formation of the chondrules — lightning, or collisions between rocks — but this new evidence tips the balance toward shockwaves as an explanation.

This explanation may be the key to understanding a persistent finding that has bedeviled scientists for decades, involving a category of elements that are “moderately volatile,” including potassium and rubidium. The Earth has less of these elements than scientists would expect, based on their general understanding of how the solar system formed. They knew the explanation could be traced to some complex chain of heating and cooling, but no one know the exact sequence. “It’s a huge question in the field of cosmochemistry.” said Dauphas.

Now, finally, the team is happy to have put a significant dent in the mystery.

“We know other processes happened — this is just one part of the story — but this really solves one step in the formation of planets,” said Hopp.

Nie agreed: “It’s really cool to be able to say quantitatively, this is what happened.”

Other co-authors on the paper were from the Carnegie Institution for Science and the University of Washington.

We would love to give thanks to the writer of this write-up for this amazing material

Beads of glass in meteorites help scientists piece together how solar system formed

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